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Application of Modern Technologies to Concept of Production of Jigsaw Puzzle
Novotný, Michal ; Slaný, Martin (referee) ; Sedlák, Josef (advisor)
This bachelor´s thesis deals with the suggestion of the convenient technical and material variation which would be suited for the production of a puzzle. It describes attributes, purposes and use of puzzles. 3D model was created in a parametric design application called Autodesk Inventor. Then the work describes the making of the puzzle. The puzzle mould was milled into SikaBlock® M 450. The puzzle pieces were printed by 3D printer REPRAP using FDM method. In addition it deals with the alternative production of the puzzle. The technical and economic evaluation of the technical and material variations is available in the conclusion of this work.
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Attributes Calculation for Prediction of Mutation Effect on Protein Function
Šinkora, Jan ; Filák, Jakub (referee) ; Jaša, Petr (advisor)
This thesis deals with issues of bioinformatics, machine learning, algorithms and data structures. The thesis is based on existing applications, Caver and Deleterious, developed by students from the Faculty of Informatics, Masaryk University and the Faculty of Information Technology, Brno University of Technology. The Deleterious framework calculates protein attributes that are important for the prediction of the effect of protein mutations on its function. Caver is a tool that finds tunnels in the 3-dimensional model of a protein. The goal of the thesis is to extend these applications by adding more attributes to the prediction process that could lead to improved prediction. The added attributes are related to detection and measurement of protein pockets.
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Analysis of NC programming options for enclosed pockets
Janda, Jiří ; Osička, Karel (referee) ; Polzer, Aleš (advisor)
The aim of this paper is to provide an overview of the available strategies for milling of closed pockets. In particular, it focuses on advanced programming using CAM programs. In the next parts, the work is focused on the analysis of the force load of tools in the machining of the pockets. Here it focuses on the course of forces in milling at the corner of the pocket using different methods of analyzing this load. There are also ways to reduce this burden.
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Analysis of NC programming options for enclosed pockets
Janda, Jiří ; Osička, Karel (referee) ; Polzer, Aleš (advisor)
The aim of this paper is to provide an overview of the available strategies for milling of closed pockets. In particular, it focuses on advanced programming using CAM programs. In the next parts, the work is focused on the analysis of the force load of tools in the machining of the pockets. Here it focuses on the course of forces in milling at the corner of the pocket using different methods of analyzing this load. There are also ways to reduce this burden.
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|
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Application of Modern Technologies to Concept of Production of Jigsaw Puzzle
Novotný, Michal ; Slaný, Martin (referee) ; Sedlák, Josef (advisor)
This bachelor´s thesis deals with the suggestion of the convenient technical and material variation which would be suited for the production of a puzzle. It describes attributes, purposes and use of puzzles. 3D model was created in a parametric design application called Autodesk Inventor. Then the work describes the making of the puzzle. The puzzle mould was milled into SikaBlock® M 450. The puzzle pieces were printed by 3D printer REPRAP using FDM method. In addition it deals with the alternative production of the puzzle. The technical and economic evaluation of the technical and material variations is available in the conclusion of this work.
|
|
|
Attributes Calculation for Prediction of Mutation Effect on Protein Function
Šinkora, Jan ; Filák, Jakub (referee) ; Jaša, Petr (advisor)
This thesis deals with issues of bioinformatics, machine learning, algorithms and data structures. The thesis is based on existing applications, Caver and Deleterious, developed by students from the Faculty of Informatics, Masaryk University and the Faculty of Information Technology, Brno University of Technology. The Deleterious framework calculates protein attributes that are important for the prediction of the effect of protein mutations on its function. Caver is a tool that finds tunnels in the 3-dimensional model of a protein. The goal of the thesis is to extend these applications by adding more attributes to the prediction process that could lead to improved prediction. The added attributes are related to detection and measurement of protein pockets.
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